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Updated: May 12, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
[Stevens-Johnson syndrome: presentation of a case of fever and a rash]
J Martínez-Pérez1, D Caldevilla-Bernardo, R Perales-Pardo
1Complejo Hospitalario Universitario de Albacete, Albacete, España.
Abstract:
Stevens-Johnson syndrome is a rare acute process with a mortality rate of 20%. Stevens-Johnson syndrome is a reactive dermatosis consisting of an erythema multiforme with the presence of vesicles and or blisters in the mucosa (particularly oral). Its more severe presentation is toxic epidermal necrolysis. The most frequent cause is hypersensitivity to multiple drugs, followed by infections, connective tissue diseases, and neoplasms. Although it is a rare syndrome, we must consider it, as the rapid installation of an appropriate treatment, as well as the rapid withdrawal of the triggering drug, can considerably reduce the morbidity and mortality.
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