Related Experiment Video
Updated: May 12, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
Multilevel predictors of colorectal cancer screening use in California
Salma Shariff-Marco1, Nancy Breen, David G Stinchcomb
1Cancer Prevention Institute of California, Fremont, CA 94538, USA. salma.shariff-marco@cpic.org
Background:
Screening can detect colorectal cancer (CRC) early, yet its uptake needs to be improved. Social determinants of health (SDOH) may be linked to CRC screening use but are not well understood.
Objectives:
To examine geographic variation in CRC screening and the extent to which multilevel SDOH explain its use in California, the most populous and racially/ethnically diverse state in the United States.
Study Design:
Analysis of individual and neighborhood data on 20,626 adult respondents aged >50 years from the 2005 California Health Interview Survey.
Methods:
We used multilevel logistic regression models to estimate the effects of individual characteristics and area-level segregation, socioeconomic status (SES), and healthcare resources at 2 different geographic levels on CRC screening use.
Results:
We confirmed that individual-level factors (eg, race/ethnicity, income, insurance) were strong predictors and found that area-level healthcare resources were associated with CRC screening. Primary care shortage in the Medical Service Study Area was associated with CRC screening for any modality (odds ratio [OR] = 0.89; 95% confidence interval [CI], 0.80-1.00). County-level HMO penetration (OR = 1.85; 95% CI, 1.47-2.33) and primary care shortage (OR = 0.73; 95% CI, 0.53-0.99) were associated with CRC screening with flexible sigmoidoscopy.
Conclusions:
Contextual factors including locality, primary care resources, and HMO membership are important determinants of CRC screening uptake; SES and segregation did not explain variation in screening behavior. More studies of contextual factors and varying geographic scales are needed to further elucidate their impact on CRC screening uptake.
Related Concept Videos
Longitudinal Research
Cancer Survival Analysis
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
Cancer Prevention
Some...
Longitudinal Studies
