Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Engineered Co<sub>3</sub>O<sub>4</sub> nanoboxes boost luminol chemiluminescence for selective Mn<sup>2+</sup> sensing.

Nanoscale·2026

Same author

Ni-Co Layered Double Hydroxide Nanocage-Mediated Reactive Oxygen Species Generation for Ultrasensitive Chemiluminescent Detection of Dopamine.

Analytical chemistry·2025

Same author

Selective Electrochemical Biosensors for Tyrosinase and Tyramine via Enzyme-Mediated Oxidation Reaction.

Analytical chemistry·2025

Same author

Electrochemical Detection of Hydrogen Peroxide at High Concentrations Using Hastelloy G35 Electrode.

Langmuir : the ACS journal of surfaces and colloids·2025

Same author

Chemiluminescence of lucigenin-tetracycline and its application for sensitive determination of procyanidin.

Journal of food and drug analysis·2024

Same author

Signal-On Detection of Dopamine and Tyrosinase Using Tris(hydroxypropyl)phosphine as a New Lucigenin Chemiluminescence Coreactant.

Analytical chemistry·2024

Search research articles

Related Experiment Video

Updated: May 12, 2026

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

A self-powered microfluidic origami electrochemiluminescence biosensing platform.

Xiaowei Zhang¹, Jing Li, Chaogui Chen

¹State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Changchun 130022, Jilin, PR China.

Chemical Communications (Cambridge, England)

|April 3, 2013

Summary

Researchers developed a novel self-powered 3D microfluidic biosensing platform using origami principles. This eco-friendly device integrates a primary battery, enabling portable electrochemiluminescence detection without noble metals.

More Related Videos

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Published on: February 23, 2020

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

Related Experiment Videos

Last Updated: May 12, 2026

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Published on: February 23, 2020

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

Area of Science:

Biomedical Engineering
Analytical Chemistry
Materials Science

Background:

Biosensing platforms are crucial for detecting biomarkers.
Existing platforms often require external power sources and expensive materials.
There is a need for portable, cost-effective, and sustainable biosensing solutions.

Purpose of the Study:

To develop a novel self-powered 3D microfluidic electrochemiluminescence (ECL) biosensing platform.
To integrate a stable, environmentally-friendly, and noble metal-free primary battery.
To utilize the principle of origami for platform fabrication.

Main Methods:

Fabrication of a 3D microfluidic device using origami techniques.
Integration of a primary battery as a self-powering component.
Development of an electrochemiluminescence detection system compatible with the platform.

Main Results:

Successful development of a self-powered 3D microfluidic biosensing platform.
Demonstration of a stable and environmentally-friendly primary battery.
Achieved electrochemiluminescence detection without the use of noble metals.

Conclusions:

The developed origami-based platform offers a novel approach to portable biosensing.
The integration of a primary battery provides a self-powered solution.
The elimination of noble metals enhances sustainability and reduces cost.