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Updated: May 12, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

[3-dimensional speckle tracking echocardiography for left ventricular rotation and twist in patients with

Wenhui Zhu1, Yan Tong, Wengang Liu

  • 1Department of Ultrasonography, Third Xiangya Hospital, Central South University, Changsha 410013, China.

Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences
|April 3, 2013
PubMed

Insights

Essential hypertension (EH) affects left ventricular rotation and twist differently based on configuration. Three-dimensional speckle tracking echocardiography (3D-STE) reveals these changes and impacts on systolic function.

Area of Science:

  • Cardiology
  • Echocardiography
  • Hypertension Research

Background:

  • Essential hypertension (EH) is a major cardiovascular risk factor.
  • Left ventricular (LV) remodeling occurs in EH, altering cardiac mechanics.
  • Understanding LV rotation and twist is crucial for assessing systolic function in EH.

Purpose of the Study:

  • To analyze left ventricular (LV) rotation and twist characteristics in patients with essential hypertension (EH) across different LV configurations.
  • To utilize 3-dimensional speckle tracking echocardiography (3D-STE) for this analysis.
  • To correlate these mechanical changes with LV systolic function.

Main Methods:

  • 106 EH patients were categorized into four groups: normal configuration (LVN), concentric remodeling (CCR), concentric hypertrophy (CCH), and eccentric hypertrophy (ECH).
  • A control group of 30 healthy subjects was included for comparison.
  • Key parameters including LV ejection fraction (LVEF), peak basal rotation (Prot-B), peak apical rotation (Prot-A), LV rotation (LV-rot), and LV twist (LV-tw) were measured using 3D-STE.

Main Results:

  • Left ventricular mass index was significantly higher in all EH groups compared to controls.
  • CCH and CCR groups showed increased LV posterior wall thickness, interventricular septum thickness, and relative wall thickness.
  • LVEF was preserved in LVN, CCR, and CCH groups but reduced in the ECH group. LV rotation and twist parameters were elevated in LVN, CCR, and CCH groups but decreased in the ECH group compared to controls.

Conclusions:

  • 3D-STE is effective in evaluating left ventricular rotation and twist in EH patients with diverse LV configurations.
  • These echocardiographic parameters can reflect alterations in LV systolic function associated with different EH-induced LV remodeling patterns.
  • Findings highlight the utility of 3D-STE in characterizing complex mechanical changes in hypertensive heart disease.
Abstract

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