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Published on: February 10, 2023
Cerebral venous thrombosis in ulcerative colitis.
Bindu Menon1, Rajeev Goyal, Lalit Nihal
1Department of Neurology, Narayana Medical College and Superspeciality Hospital, Nellore, Andhra Pradesh, India.
Journal of Neurosciences in Rural Practice
|April 3, 2013
Summary
Ulcerative colitis patients may experience hypercoagulation, increasing thrombosis risk. This case highlights cerebral venous thrombosis in a patient with ulcerative colitis, emphasizing the need for early diagnosis and treatment.
Area of Science:
- Gastroenterology
- Neurology
- Hematology
Background:
- Ulcerative colitis (UC) is an inflammatory bowel disease associated with a hypercoagulable state.
- Thrombosis, including peripheral and central venous events, can occur in patients with UC.
- Cerebral venous thrombosis (CVT) is a rare but serious complication.
Observation:
- A 35-year-old female presented with symptoms of active ulcerative colitis.
- Following diagnosis and initiation of UC treatment, the patient developed neurological symptoms including headache and seizures.
- Brain MRI revealed cerebral venous thrombosis with venous infarcts.
Findings:
- The patient was diagnosed with ulcerative colitis and subsequently developed cerebral venous thrombosis.
- This case illustrates a rare neurological complication in the context of active inflammatory bowel disease.
- Hypercoagulation in UC may predispose to central thrombosis events.
Implications:
- A high index of clinical suspicion is crucial for diagnosing CVT in UC patients.
- Prompt diagnosis and management of CVT are essential to prevent severe neurological sequelae.
- Understanding the link between UC and hypercoagulation may improve patient monitoring and risk stratification.
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