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Clostridium difficile infection in the hospitalized pediatric population: increasing trend in disease incidence

Abhishek Deshpande1, Chaitanya Pant, Michael P Anderson

  • 1From the *Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH; †Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK; ‡Research Service, Cleveland Veterans Affairs Medical Center; and §Department of Pediatrics, Case Western Reserve University School of Medicine, UH Rainbow Babies & Children's Hospital, Cleveland, OH.

The Pediatric Infectious Disease Journal
|April 3, 2013
PubMed

Insights

The incidence of Clostridium difficile infection in hospitalized children is increasing. Greater efforts are needed to prevent and treat this infection in pediatric patients.

Area of Science:

  • Pediatric Infectious Diseases
  • Healthcare Epidemiology

Background:

  • Clostridium difficile infection (CDI) is a significant cause of hospital-acquired infections.
  • Understanding trends in pediatric CDI is crucial for public health.

Purpose of the Study:

  • To assess the incidence trend of Clostridium difficile infection in hospitalized children in the United States.
  • To evaluate changes in CDI rates among pediatric inpatients from 2003 to 2009.

Main Methods:

  • Utilized data from a United States national inpatient database.
  • Analyzed trends in Clostridium difficile infection incidence over a seven-year period (2003-2009).

Main Results:

  • Observed a statistically significant increasing trend in the incidence of Clostridium difficile infection among hospitalized pediatric patients.
  • The data indicate a rise in CDI cases within this demographic during the study period.

Conclusions:

  • The incidence of Clostridium difficile infection continues to rise in hospitalized children.
  • Enhanced strategies for prevention and treatment of pediatric CDI are urgently required.

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