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Immediate skin sensitivity test reactivity in Nigerians with allergic rhinitis

A O Ibekwe1, B C Okafor, G O Okafor

  • 1Department of Otolaryngology, University of Nigeria Teaching Hospital, Enugu.

East African Medical Journal
|January 1, 1990
PubMed

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Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...