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Lobomycosis successfully treated with posaconazole.
Beatriz Bustamante1, Carlos Seas, Martín Salomon
1Departamento de Enfermedades Infecciosas, Tropicales y Dermatológicas, Hospital Nacional Cayetano Heredia, Lima, Peru. ana.bustamante@upch.pe
The American Journal of Tropical Medicine and Hygiene
|April 3, 2013
Summary
Lobomycosis, a chronic fungal infection, has no standard treatment. A patient in Peru achieved successful treatment with posaconazole over 27 months, with no recurrence after five years.
Area of Science:
- Mycology
- Infectious Diseases
- Dermatology
Background:
- Lobomycosis is a neglected tropical fungal infection affecting the skin and subcutaneous tissues.
- Currently, no universally accepted standard treatment exists for lobomycosis, posing a significant clinical challenge.
Observation:
- A case study from Peru details a patient presenting with lobomycosis localized to the left earlobe.
Findings:
- The patient received posaconazole treatment for a duration of 27 months.
- Successful treatment was confirmed by the absence of clinical signs and symptoms.
- Long-term follow-up for five years revealed no evidence of disease recurrence.
Implications:
- This case suggests posaconazole as a potential therapeutic option for lobomycosis.
- Further research into posaconazole's efficacy and safety for lobomycosis is warranted.
- This finding may guide future treatment strategies for this chronic mycosis.
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