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Does left ventricular aneurysm influence survival after acute myocardial infarction?
1Department of Medicine, Hospital Clinic i Provincial, University of Barcelona, Spain.
European Heart Journal
|May 1, 1990
Summary
Left ventricular aneurysm does not independently predict survival after acute myocardial infarction. After adjusting for other factors, survival rates were similar in patients with and without this condition.
Area of Science:
- Cardiology
- Clinical Medicine
- Medical Research
Background:
- Left ventricular aneurysm (LVA) is a potential complication following acute myocardial infarction (AMI).
- The independent impact of LVA on long-term survival after AMI remains a subject of investigation.
Purpose of the Study:
- To determine if left ventricular aneurysm independently influences survival rates in patients who have experienced an acute myocardial infarction.
- To identify other key predictors of survival in this patient population.
Main Methods:
- A cohort of 386 male patients under 60 years old, post-AMI, were followed for a median of 57 months.
- Left ventricular aneurysm was diagnosed via catheterization in 52 patients (13.5%).
- Cox regression analysis was used to identify independent predictors of survival, with matched-pair analysis performed for LVA patients.
Main Results:
- Initially, patients with LVA showed higher mortality (29% vs 14%).
- However, after adjusting for ejection fraction, bifascicular block, diseased vessels, and post-infarction angina, LVA was not an independent predictor of survival.
- Matched-pair analysis confirmed similar survival rates between LVA patients and controls (75% vs 82% mortality).
Conclusions:
- Left ventricular aneurysm is not an independent predictor of mortality after acute myocardial infarction.
- Ejection fraction, bifascicular block, number of diseased vessels, and angina are significant independent predictors of survival post-AMI.
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