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Related Experiment Video

Updated: May 12, 2026

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
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Spinal cord stimulation in cluster headache.

Tilman Wolter1, Holger Kaube

  • 1Interdisciplinary Pain Centre, University Hospital Freiburg, Breisacherstr. 64,79106 Freiburg, Germany. tilman.wolter@uniklinik-freiburg.de

Current Pain and Headache Reports
|April 3, 2013
PubMed
Summary
This summary is machine-generated.

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Neurostimulation offers new hope for chronic cluster headache (CCH). Occipital nerve stimulation (ONS) is effective, while spinal cord stimulation (SCS) shows emerging promise for this debilitating condition.

Area of Science:

  • Neurology
  • Neurosurgery
  • Pain Management

Background:

  • Chronic cluster headache (CCH) is a severe primary headache syndrome.
  • Refractory CCH poses significant treatment challenges.
  • Neurostimulation is an evolving therapeutic area for CCH.

Purpose of the Study:

  • To review current clinical research on neurostimulation for CCH.
  • To compare the efficacy and limitations of different neurostimulation techniques.
  • To highlight occipital nerve stimulation (ONS) and spinal cord stimulation (SCS).

Main Methods:

  • Review of existing clinical studies and literature.
  • Analysis of outcomes for ONS and SCS in CCH patients.
  • Comparative assessment of neurostimulation modalities.

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Main Results:

  • Occipital nerve stimulation (ONS) demonstrates favorable clinical results for refractory CCH.
  • ONS is becoming a standard treatment in specialized centers.
  • Spinal cord stimulation (SCS) and sphenopalatine ganglion stimulation are emerging techniques.

Conclusions:

  • Neurostimulation, particularly ONS, is a valuable option for refractory CCH.
  • Further research is needed to fully establish the role of SCS and other emerging techniques.
  • Pros and cons of ONS and SCS require careful consideration for patient selection.