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[Coexistence of systemic sclerosis and gout? Hyperuricemia in systemic sclerosis: case report and literature review]

Marta Madej1, Ewa Morgiel, Anna Łuczak

  • 1Katedra i Klinika Reumatologii i Chorób Wewnetrznych Akademii Medycznej we Wrocławiu ul. Borowska 213, 50-556 Wrocław.

Annales Academiae Medicae Stetinensis
|April 4, 2013
PubMed

Insights

Systemic sclerosis may coexist with gout, a condition marked by elevated uric acid levels. This association may impact cardiovascular prognosis in patients with systemic sclerosis.

Area of Science:

  • Rheumatology
  • Internal Medicine

Background:

  • Systemic sclerosis is a chronic autoimmune disease with limited reports on its coexistence with gout.
  • Gout, a common arthritis in men over 40, is linked to hyperuricemia, metabolic syndrome, diuretics, and cardiovascular disease.

Observation:

  • A 47-year-old male with systemic sclerosis, interstitial lung disease, and hypertension presented with hyperuricemia.
  • Clinical examination revealed tophi-like nodules on the elbow and knee, with radiographic evidence of calcifications.

Findings:

  • The case highlights the coexistence of systemic sclerosis and gout in a patient with hyperuricemia.
  • Elevated uric acid levels may influence the prognosis of systemic sclerosis, especially concerning cardiovascular complications.

Implications:

  • Clinicians should consider gout in systemic sclerosis patients with hyperuricemia.
  • Hyperuricemia's role in cardiovascular and pulmonary arterial hypertension in systemic sclerosis warrants further investigation.
Abstract

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