[Genetic strains of Hansenula polymorpha]

Six centromeric linkage groups and four non-centromeric fragments are revealed in the genetic stocks of Hansenula polymorpha which were obtained by intratetrad breeding in several generations of two genetically different parental strains progeny. Fourteen nuclear markers are mapped, including auxotrophic mutations, mating regulation loci, determinants of sporulation and heat tolerance. Complex origin of the haploid genome of these stocks leads to affinity interactions and to 14 per cent increase in DNA content in haploid stocks, as compared with the parental strains.