Related Experiment Video
Updated: May 12, 2026

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
Published on: August 30, 2011
Loss of person-specific knowledge in Alzheimer's disease: evidence from priming
David Predovan1, Delphine Gandini, Maxime Montembeault
1a Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal , Montréal , Canada.
Abstract:
Semantic deficits in Alzheimer's disease (AD) are often more severe for items that are characterized by a unique semantic and lexical association, such as famous people. Whether these deficits are due to the degradation of semantic information or a deficit in the ability to intentionally access semantic knowledge remains controversial. To assess the integrity of the semantic system without explicitly accessing it, a priming paradigm was used. Semantic and repetition priming effects in individuals with AD (n = 7) and age-matched controls (n = 13) were measured in a familiarity judgment task using visually-presented names of famous people. A defective priming effect in AD subjects was observed in the semantic priming but not in the repetition priming condition. Therefore, the semantic impairments observed in AD may indicate a degraded representation of the semantic information concerning famous people.
More Related Videos
06:23The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
Published on: October 13, 2016
09:45Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke
Published on: March 22, 2016
Related Concept Videos
Alzheimer Disease l: Introduction
Alzheimer Disease ll: Pathophysiology
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Implicit Memories
One key aspect of implicit...
Dementia l: Introduction
Automatic Processing and Automatic Social Behavior