Related Experiment Video
Updated: May 12, 2026
12:43
A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)
Published on: February 21, 2011
Speech disturbances due to left precentral cortical lesions
1a Division of Neurology, Department of Medicine , Tokyo Metropolitan Ohtsuka Hospital , Toshima-ku , Japan.
Neurocase
|April 4, 2013
Summary
Lesions in the left precentral cortex can cause diverse speech disorders, affecting either prosody or articulation. This highlights the nuanced role of this brain region in speech production.
Area of Science:
- Neurology
- Speech Pathology
- Neuroscience
Background:
- The left precentral cortex is crucial for motor control, including speech production.
- Understanding the precise localization of lesions within this area is key to predicting specific speech deficits.
Observation:
- Two patients presented with speech disorders attributed to lesions in the left precentral cortex.
- Patient 1 had an anterior lesion affecting prosody.
- Patient 2 had a posterior and inferior lesion affecting articulation.
Findings:
- Lesion location within the left precentral cortex correlates with distinct speech disturbances.
- Anterior lesions impacted prosody, while more posterior/inferior lesions affected articulation.
- Speech disorders manifest differently even with similar lesion locations.
Implications:
- Precise lesion mapping in the precentral cortex can aid in diagnosing and managing speech disorders.
- This study refines our understanding of the functional neuroanatomy of speech.
- Further research can explore the neural pathways underlying prosody and articulation.
Related Concept Videos
01:10Higher Mental Functions of the Brain: Language
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
01:28Lateralization
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
01:30Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
01:05Cerebral Hemispheres
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
01:14Motor and Sensory Areas of the Cortex
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
01:14Role of Cerebellum and Prefrontal Cortex in Memory
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...