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Related Concept Videos

Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...
Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
Skeletal Muscle Anatomy00:55

Skeletal Muscle Anatomy

Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.

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The In ovo CAM-assay as a Xenograft Model for Sarcoma
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Published on: July 17, 2013

Intramuscular, extraskeletal mesenchymal chondrosarcoma.

Manjula Jain1, Vandana Puri, Neha Kawatra Madan

  • 1Department of Pathology, Lady Hardinge Medical College and Smt. Sucheta Kriplani Hospital, New Delhi, India.

Indian Journal of Medical Sciences
|April 4, 2013
PubMed
Summary

Extraskeletal mesenchymal chondrosarcoma (EMC) is a rare malignant tumor. This case highlights diagnostic challenges of EMC in unusual intramuscular locations, emphasizing the need for accurate differentiation from other small cell neoplasms.

Area of Science:

  • Oncology
  • Pathology
  • Skeletal System Neoplasms

Background:

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  • Extraskeletal mesenchymal chondrosarcoma (EMC) is a rare malignant chondrogenic neoplasm.
  • EMC typically arises outside of bone, with intramuscular locations being exceptionally uncommon.
  • Accurate diagnosis is challenging, particularly when cartilaginous differentiation is minimal, complicating distinction from other small cell neoplasms.