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Updated: May 12, 2026

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
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Published on: February 22, 2020

Does exercise tolerance testing at 60 days poststroke predict rehabilitation performance?

Dorian K Rose1, Andrea L Behrman, Stephen E Nadeau

  • 1Department of Physical Therapy, University of Florida, Gainesville, FL, USA. dkrose@phhp.ufl.edu

Archives of Physical Medicine and Rehabilitation
|April 4, 2013
PubMed
Summary
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Cardiovascular fitness assessed by exercise tolerance tests (ETT) post-stroke did not uniquely predict progress in locomotor training. The 6-minute walk test (6MWT) showed similar predictive power, suggesting neurological factors are more influential.

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Exercise Physiology

Background:

  • Stroke survivors often experience impaired mobility, necessitating targeted rehabilitation programs.
  • Locomotor training aims to improve walking ability after stroke.
  • Assessing predictors of rehabilitation success is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To evaluate the relationship between exercise tolerance test (ETT) performance at six weeks post-stroke and subsequent success in a locomotor training program (LTP).

Main Methods:

  • A prospective cohort study involving 469 community-dwelling individuals post-stroke.
  • Participants were enrolled in the Locomotor Experience Applied Post-Stroke trial.
  • Regression analyses examined the influence of ETT performance (cycling duration), age, and 6-minute walk test (6MWT) distance on achieving a 20-minute stepping goal in LTP.

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Main Results:

  • Individually, age, 6MWT distance, and ETT performance each explained approximately 10.7-10.8% of the variance in sessions needed to reach the stepping goal.
  • When age and 6MWT were considered, the unique contribution of ETT performance to predicting training progress became non-significant (P=.150).

Conclusions:

  • Cardiovascular fitness, as measured by ETT, does not appear to be a unique predictor of locomotor training success post-stroke.
  • The 6-minute walk test (6MWT), potentially reflecting neurological and muscular status, demonstrated comparable predictive value to ETT.
  • These findings suggest that factors beyond cardiovascular fitness significantly influence recovery of walking function after stroke.