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[Cardiovascular risk profile of patients with psoriasis]

Daniela Di Lisi, Francesca Macaione, Egle Corrado

    Recenti Progressi in Medicina
    |April 4, 2013
    PubMed

    Insights

    Patients with psoriasis have a higher cardiovascular risk profile. This study found psoriasis patients exhibited increased risks for hypertension, unfavorable lipid profiles, diabetes, and metabolic syndrome compared to controls.

    Area of Science:

    • Cardiology
    • Dermatology
    • Metabolic Health

    Background:

    • Psoriasis is a chronic inflammatory disease with known associations to systemic conditions.
    • Cardiovascular disease is a leading cause of mortality, and understanding risk factors is crucial.

    Purpose of the Study:

    • To compare the cardiovascular risk profile between patients diagnosed with psoriasis and those without the condition.
    • To investigate the prevalence of hypertension, dyslipidemia, diabetes, and obesity in psoriasis patients.

    Main Methods:

    • A case-control study design was employed.
    • 143 patients with psoriasis (cases) and 104 patients without psoriasis (controls) were included.
    • Key cardiovascular risk factors including hypertension, lipid profiles (HDL, triglycerides), diabetes, and body mass index were assessed.

    Main Results:

    • Psoriasis patients demonstrated a significantly less favorable cardiovascular risk profile compared to the control group.
    • The prevalence of hypertension, dyslipidemia, and diabetes was higher in the psoriasis cohort.
    • Psoriasis patients exhibited a greater risk for developing cardiovascular events and metabolic syndrome.

    Conclusions:

    • Psoriasis is associated with an increased burden of cardiovascular risk factors.
    • These findings highlight the importance of proactive cardiovascular risk assessment and management in patients with psoriasis.
    • Integrated care approaches addressing both dermatological and cardiovascular health are warranted for psoriasis patients.

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