Catheter ablation of ventricular arrhythmias: targets, tactics, and tools

Jeffrey R Winterfield1, Srijoy Mahapatra, David J Wilber

  • 1Cardiovascular Institute, Loyola University Medical Center, Maywood, Illinois 60153, USA. jwinterfield@lumc.edu

Insights

Catheter ablation effectively suppresses drug-refractory ventricular tachycardia in structural heart disease. Advances in imaging and mapping technologies improve outcomes for this complex arrhythmia.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Technology

Background:

  • Drug-refractory ventricular tachycardia (VT) in structural heart disease (SHD) leads to frequent implantable cardioverter-defibrillator (ICD) shocks and heart failure.
  • Management of VT in SHD necessitates catheter ablation for effective arrhythmia suppression.

Purpose of the Study:

  • To review the evolution and current state of catheter ablation for VT in structural heart disease.
  • To highlight the impact of new imaging and mapping technologies on ablation outcomes.

Main Methods:

  • Review of recent advancements in imaging modalities (e.g., MRI, CT) for characterizing myocardial substrate.
  • Integration of electroanatomic mapping (EAM) with imaging data for precise VT circuit localization.
  • Evaluation of novel ablation technologies and strategies for targeting complex VT substrates.

Main Results:

  • Advanced imaging and EAM provide critical insights into the structural abnormalities underlying VT.
  • Integrating imaging with 3D mapping systems enhances the targeting of abnormal electrical signals, potentially improving ablation success.
  • Emerging ablation tools demonstrate promise in treating VT circuits previously considered unreachable.

Conclusions:

  • Catheter ablation for VT has significantly evolved over the past two decades.
  • Technological improvements in imaging, mapping, and ablation tools are poised to increase the utilization of catheter ablation for VT in structural heart disease.
Abstract

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