Migraine associated with periorbital ecchymosis

Area of Science:

• Neurology
• Ophthalmology

Background:

• Migraine is a common neurological disorder.
• Periorbital ecchymosis is typically associated with trauma or specific medical conditions.

Observation:

• Two patients presented with periorbital ecchymosis.
• The onset of ecchymosis coincided with migraine episodes.

Findings:

• The association between periorbital ecchymosis and migraine is exceedingly rare.
• This phenomenon was last documented in medical literature nearly a century ago.

Implications:

• Understanding this rare association may aid in diagnosing complex migraine presentations.
• Further research into the pathophysiology linking migraine and periorbital ecchymosis is warranted.