Related Experiment Video
Updated: May 12, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
Published on: March 23, 2014
Leprosy and its dental management guidelines.
1Centre for International Child Oral Health, King's College London, London, UK. bellad@doctors.org.uk
Leprosy patients exhibit significant orofacial manifestations, including nerve involvement, necessitating specialized dental care. A new clinical protocol guides dentists in managing these oral health issues in leprosy patients.
Area of Science:
- Oral Medicine
- Infectious Diseases
- Dermatology
Background:
- Leprosy, caused by Mycobacterium leprae, is a chronic disease affecting skin, nerves, and orofacial structures.
- Orofacial manifestations include alveolar bone destruction and tooth loss, impacting dental health.
Purpose of the Study:
- To evaluate orofacial manifestations in leprosy patients at the Bombay Leprosy Project.
- To develop clinical guidelines for dentists managing leprosy patients.
Main Methods:
- A cross-sectional study involving 43 diagnosed leprosy patients.
- Questionnaires assessed oral health status and hygiene; clinical examinations included extra-oral and intra-oral assessments.
Main Results:
- 84% of patients were male, mean age 35.9 years.
- 49% had extra-oral lesions, 28% had intra-oral lesions (e.g., hyperpigmented patches).
- 21% experienced cranial nerve involvement, most commonly the trigeminal nerve.
Conclusions:
- A clinical dental pathway protocol was developed for leprosy patients.
- Highlights the importance of dental management and cranial nerve examination.
- Low infectivity allows standard infection control measures in dental settings.
More Related Videos
Related Concept Videos
Endocarditis III: Medical Management
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Rheumatic Heart Disease III: Medical Management
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Tonsillitis II: Management

