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Updated: May 12, 2026
08:33
Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
Published on: December 11, 2016
Summary
Exertional rhabdomyolysis, a condition caused by physical exertion and heat stress, affected 402 U.S. service members in 2012. Rates increased 30% from 2008-2012, with highest risks in young, male, Black, non-Hispanic service members and specific military branches.
Area of Science:
- Military Medicine
- Environmental Health
- Musculoskeletal Disorders
Background:
- Exertional rhabdomyolysis (ER) is a serious condition linked to physical exertion and heat stress.
- Understanding ER incidence and risk factors in military populations is crucial for prevention and treatment.
Purpose of the Study:
- To analyze the incidence and trends of ER among U.S. service members from 2008 to 2012.
- To identify demographic, occupational, and geographic risk factors associated with ER.
Main Methods:
- Retrospective analysis of incident ER cases among U.S. service members in 2012.
- Examination of annual incidence rate trends from 2008 to 2012.
- Stratification of incidence rates by demographic, military, and geographic factors.
Main Results:
- In 2012, 402 ER episodes occurred, with a 30% increase in annual rates from 2008-2012.
- Highest incidence rates were observed in males, Black, non-Hispanic service members, those under 20, Army/Marine Corps members, recruits, and those in combat roles.
- Elevated rates were noted in service members from the Northeast, with diagnoses concentrated at training installations and combat unit locations.
Conclusions:
- ER poses a significant risk to U.S. service members, particularly recruits and those in physically demanding roles.
- Risk factors include specific demographics, military branches, and geographic locations.
- Medical providers should consider ER in differential diagnoses for service members presenting with relevant symptoms after strenuous activity, especially in hot, humid conditions.
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