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Related Experiment Video

Updated: May 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Alliaceous migraines.

Alexander P Roussos¹, Alan R Hirsch

¹Smell and Taste Treatment and Research Foundation, Chicago, IL, USA.

|April 5, 2013

Summary

This summary is machine-generated.

This case study details a rare instance of migraines with aura triggered by both garlic and onion aromas in a single patient. Interventions like nose plugs and peppermint stimulation proved effective in preventing these debilitating odor-induced headaches.

Keywords:

alliaceous aroma garlic headache migraine onion

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Area of Science:

Neurology
Ophthalmology
Allergology

Background:

Odors are known migraine triggers in 70% of patients, but alliaceous aromas are rarely reported.
Multiple alliaceous odors as triggers in one individual and their association with migraine with aura are not well-documented.

Observation:

A 32-year-old woman experienced severe migraines with aura, including visual disturbances and intense headaches, triggered by garlic and onion aromas.
Symptoms included panic attacks, throat constriction, photophobia, phonophobia, and various other neurological and sensory disturbances.
The patient also reported chemosensory issues like dysosmias and metallic taste.

Findings:

Neurological examination revealed bilateral positive Hoffman reflexes; other tests were normal.
Allergy skin tests were positive for garlic and onion.
Nose plugs and peppermint stimulation successfully prevented headache onset.

Implications:

This is the first reported case of migraine with aura triggered by multiple alliaceous compounds.
Potential mechanisms include odor-induced emotional changes, neurogenic inflammation, and allergic responses.
Counter-stimulation and nasal occlusion may be beneficial for managing such cases.