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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Challenges to the global control of tuberculosis
Chen-Yuan Chiang1, Catharina Van Weezenbeek, Toru Mori
1International Union Against Tuberculosis and Lung Disease, 68 Boulevard Saint-Michel, Paris, France. cychiang@theunion.org
Respirology (Carlton, Vic.)
|April 5, 2013
Summary
Global tuberculosis (TB) control faces challenges despite new diagnostic tools. Addressing operational and cost issues is crucial for effective multidrug-resistant TB (MDR-TB) management and treatment success.
Area of Science:
- Public Health
- Infectious Diseases
- Global Health
Background:
- Tuberculosis (TB) control is at a critical juncture with emerging management paradigms.
- Global TB control remains a significant challenge, with low case detection rates and a high burden of multidrug-resistant TB (MDR-TB).
Purpose of the Study:
- To highlight the challenges in diagnosing and treating TB, particularly MDR-TB.
- To emphasize the need for operational and cost-effective solutions for new diagnostic tools.
- To advocate for improved health systems and intersectoral collaboration for TB elimination.
Main Methods:
- Analysis of global TB and MDR-TB case detection and notification data from 2011.
- Review of treatment success rates for MDR-TB.
- Assessment of the scale-up of programmatic management of drug-resistant TB.
Main Results:
- In 2011, the global TB case detection rate was 66%, with an estimated 310,000 MDR-TB cases.
- Programmatic management of drug-resistant TB scale-up was slow, with only 60,000 MDR-TB cases notified in 2011.
- MDR-TB treatment success rates in 2009 were 48%, significantly below the 75% target.
Conclusions:
- New diagnostic and treatment tools show promise but face operational and cost barriers.
- Strengthening health systems and human resources is essential for effective TB control.
- Intersectoral collaboration and advocacy for cost reduction are vital for TB elimination efforts.
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