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Pruritic papular eruption in HIV: a case successfully treated with NB-UVB
Sara Bellavista1, Antonietta D' Antuono, Salvatore Domenico Infusino
1Section of Dermatology and Venereology, Department of Internal Medicine, Geriatrics and Nephrology, University of Bologna, Bologna, Italy. sara.bellavista4@unibo.it
Dermatologic Therapy
|April 5, 2013
Summary
Pruritic papular eruption (PPE) in HIV patients often requires symptomatic treatment. Narrow-band ultraviolet B phototherapy provided a speedy and effective solution for a patient resistant to other treatments.
Area of Science:
- Dermatology
- Infectious Diseases
- Immunology
Background:
- Pruritic papular eruption (PPE) is a common dermatosis in advanced HIV infection.
- Antiretroviral therapy (ART) often improves PPE, but persistent cases require symptomatic management.
- Current treatments for persistent PPE lack a definitive, elective option.
Observation:
- A case of recalcitrant PPE in an HIV-positive patient is presented.
- The patient's PPE did not improve with ART and was resistant to topical steroids and oral antihistamines.
- Narrow-band ultraviolet B (NB-UVB) phototherapy was administered.
Findings:
- NB-UVB phototherapy achieved a satisfactory and rapid resolution of PPE.
- This suggests NB-UVB as a potential effective treatment for refractory PPE in HIV patients.
Implications:
- NB-UVB phototherapy may be a valuable therapeutic option for managing persistent and treatment-resistant PPE in HIV-infected individuals.
- Further research into NB-UVB phototherapy for HIV-associated dermatoses is warranted.
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