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Updated: May 12, 2026
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Stroke care organization overcomes the deleterious 'weekend effect' on 1-month stroke mortality: a population-based
Y Béjot1, C Aboa-Eboulé, A Jacquin
1Dijon Stroke Registry, Department of Neurology, University Hospital and Medical School of Dijon, University of Burgundy, Burgundy, France. ybejot@yahoo.fr
European Journal of Neurology
|April 5, 2013
Summary
Implementing a dedicated stroke care network eliminated the increased risk of weekend stroke mortality. This quality improvement initiative reduced early death disparities for stroke patients, demonstrating the network
Area of Science:
- Neurology
- Public Health
- Health Services Research
Background:
- Weekend stroke onset is linked to poorer patient prognosis.
- Previous studies indicate higher mortality rates for weekend strokes.
- The impact of organized stroke care on weekend mortality was previously unevaluated.
Purpose of the Study:
- To evaluate the effect of a dedicated stroke care network on 30-day mortality.
- To assess changes in weekend/bank holiday stroke and transient ischaemic attack (TIA) mortality after network implementation.
- To analyze mortality trends stratified by stroke subtype and time period.
Main Methods:
- Population-based registry analysis of stroke and TIA cases (1985-2010).
- Cox regression models assessed the association between day of onset and 30-day mortality.
- Data were stratified by time period (pre- and post-stroke network implementation) and stroke subtype.
Main Results:
- Weekend stroke/TIA onset was associated with excess mortality before 2003 (18.2% vs. 14.0%, P < 0.01).
- This excess mortality risk (aHR 1.26) disappeared after network implementation (2004-2010, P = 0.97).
- No significant difference in 30-day mortality was observed between weekday and weekend strokes post-network implementation.
Conclusions:
- A dedicated stroke care network effectively eliminated the increased early mortality risk associated with weekend/bank holiday strokes.
- Quality improvement initiatives are crucial for mitigating inequalities in stroke patient management.
- The findings support the widespread implementation of organized stroke care networks.
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