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Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis
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Association between ED in ankylosing spondylitis: a population-based study.

S-D Chung1, Y-K Chen, S-P Liu

  • 11] Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, Ban Ciao, Taipei, Taiwan [2] Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan [3] Sleep Research Center, Taipei Medical University Hospital, Taipei, Taiwan.

International Journal of Impotence Research
|April 5, 2013
PubMed
Summary
This summary is machine-generated.

Ankylosing spondylitis (AS) is linked to erectile dysfunction (ED) in men over 40. This study found a significant association, suggesting physicians should screen AS patients for ED.

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Area of Science:

  • Rheumatology
  • Urology
  • Epidemiology

Background:

  • Ankylosing spondylitis (AS) is associated with sexual dysfunction.
  • Few studies have investigated the specific link between AS and erectile dysfunction (ED).

Purpose of the Study:

  • To examine the association between a prior diagnosis of AS and ED in a Taiwanese population.
  • To determine if AS is an independent risk factor for ED.

Main Methods:

  • Population-based case-control study.
  • 2213 male patients with ED (cases) aged ≥40 and 17,704 matched controls.
  • Multivariate logistic regression analysis adjusted for comorbidities and lifestyle factors.

Main Results:

  • A total of 224 subjects (1.1%) had a prior AS diagnosis.
  • Patients with ED had a higher prevalence of prior AS diagnosis (1.9% vs 1.0%).
  • Adjusted analysis showed a significant association between AS and ED (OR=1.58, 95% CI=1.09-2.19, P=0.019).

Conclusions:

  • There is a significant association between ankylosing spondylitis and erectile dysfunction.
  • Physicians should consider ED in male patients with AS and facilitate multidisciplinary management.
  • Further research is warranted to explore the underlying mechanisms connecting AS and ED.