Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dynamic cardiomyoplasty in patients.

G J Magovern1, S B Park, R L Kao

  • 1Department of Surgery, Allegheny General Hospital, Pittsburgh 15212-9986.

The Journal of Heart Transplantation
|May 1, 1990
PubMed
Summary

Dynamic cardiomyoplasty using latissimus dorsi muscle improved cardiac function in heart failure patients. This surgical technique shows promise for treating myocardial defects and supporting circulation in end-stage heart disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Semi-cylindrical recession trochleoplasty using 3D saw guides for canine patellar luxation.

Journal of the South African Veterinary Association·2026
Same author

Corrigendum to "Evidence of slow and variable choice-stepping reaction time in cancer survivors with chemotherapy-induced peripheral neuropathy" [Gait Posture 89 (2021) 178-185].

Gait & posture·2021
Same author

Changes in high-sensitivity C-reactive protein levels and metabolic indices according to grip strength in Korean postmenopausal women.

Climacteric : the journal of the International Menopause Society·2021
Same author

Evidence of slow and variable choice-stepping reaction time in cancer survivors with chemotherapy-induced peripheral neuropathy.

Gait & posture·2021
Same author

Magnolol induces adipogenic differentiation in human skin.

The British journal of dermatology·2020
Same author

Changes in long term peripheral nerve biophysical properties in childhood cancer survivors following neurotoxic chemotherapy.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2020

Area of Science:

  • Cardiovascular Surgery
  • Regenerative Medicine
  • Biomedical Engineering

Background:

  • Dynamic cardiomyoplasty is a surgical procedure utilizing electrically conditioned skeletal muscle to augment cardiac function.
  • This technique aims to support circulation in patients with end-stage heart disease and myocardial defects.

Observation:

  • Five patients with myocardial infarction and coronary artery disease underwent latissimus dorsi muscle implantation.
  • The muscle flap was applied to the anterolateral wall or around the ventricles, either for ventricular wall repair or functional augmentation.

Findings:

  • All patients survived the surgery, with immediate ventricular function improvement in those undergoing aneurysmectomy.
  • Three patients showed a significant increase in ejection fraction upon pacemaker activation.
  • One patient experienced sudden ventricular arrhythmia, while another showed sustained improvement over 3 years.

Implications:

  • Dynamic cardiomyoplasty demonstrates potential for improving ventricular function and supporting circulation in select heart failure patients.
  • Electrical conditioning and synchronous stimulation are key components for optimizing skeletal muscle graft performance.
  • Further research is warranted to refine surgical techniques and patient selection for cardiomyoplasty.

Related Experiment Videos