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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.

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Updated: May 12, 2026

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
10:16

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

Editorial: stem cell engineering - discovery, diagnostics and therapies.

Brenda M Ogle1, Sean P Palecek

  • 1Department of Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, WI, USA.

Biotechnology Journal
|April 5, 2013
PubMed
Summary
This summary is machine-generated.

This special issue explores stem cell engineering advancements in discovery, diagnostics, and therapies. It highlights key findings from the Third International Conference on Stem Cell Engineering.

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CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications
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Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
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Area of Science:

  • Biotechnology and Biomedical Engineering
  • Stem Cell Biology and Regenerative Medicine

Background:

  • This Special Issue compiles research presented at the Third International Conference on Stem Cell Engineering.
  • The conference was co-sponsored by the Society of Biological Engineering and the International Society for Stem Cell Research.

Discussion:

  • Focuses on the latest developments in stem cell engineering.
  • Covers applications in disease discovery, diagnostic tools, and therapeutic strategies.

Key Insights:

  • Highlights innovations in manipulating stem cells for medical purposes.
  • Showcases progress in translating stem cell research into clinical applications.

Outlook:

  • Discusses future directions in stem cell engineering research.
  • Explores the potential impact on future healthcare and therapies.