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Published on: June 23, 2023
Transmission of infection by flexible gastrointestinal endoscopy and bronchoscopy
Julia Kovaleva1, Frans T M Peters, Henny C van der Mei
1Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. j.kovaleva@umcg.nl
Abstract:
Flexible endoscopy is a widely used diagnostic and therapeutic procedure. Contaminated endoscopes are the medical devices frequently associated with outbreaks of health care-associated infections. Accurate reprocessing of flexible endoscopes involves cleaning and high-level disinfection followed by rinsing and drying before storage. Most contemporary flexible endoscopes cannot be heat sterilized and are designed with multiple channels, which are difficult to clean and disinfect. The ability of bacteria to form biofilms on the inner channel surfaces can contribute to failure of the decontamination process. Implementation of microbiological surveillance of endoscope reprocessing is appropriate to detect early colonization and biofilm formation in the endoscope and to prevent contamination and infection in patients after endoscopic procedures. This review presents an overview of the infections and cross-contaminations related to flexible gastrointestinal endoscopy and bronchoscopy and illustrates the impact of biofilm on endoscope reprocessing and postendoscopic infection.
Insights
Flexible endoscopes can harbor bacteria, forming biofilms that resist cleaning and cause infections. Microbiological surveillance is vital for detecting contamination and preventing patient infections after procedures.
Area of Science:
- Medical Microbiology
- Infection Control
- Gastroenterology and Pulmonology
Background:
- Flexible endoscopes are essential for diagnosis and therapy but pose infection risks.
- Contaminated endoscopes are linked to healthcare-associated infections.
- Complex designs with narrow channels hinder effective cleaning and disinfection.
Purpose of the Study:
- To review infections and cross-contaminations linked to flexible endoscopy.
- To highlight the impact of biofilms on endoscope reprocessing.
- To emphasize the role of microbiological surveillance in preventing infections.
Main Methods:
- Literature review of infections associated with flexible gastrointestinal endoscopy and bronchoscopy.
- Analysis of the challenges in reprocessing multi-channel endoscopes.
- Discussion of biofilm formation and its implications.
Main Results:
- Biofilm formation on endoscope channels compromises decontamination effectiveness.
- Inadequate reprocessing can lead to patient contamination and infection.
- Microbiological surveillance aids in early detection of colonization and biofilm.
Conclusions:
- Effective reprocessing of flexible endoscopes is critical to prevent patient infections.
- Biofilms present a significant challenge to standard decontamination protocols.
- Implementing microbiological surveillance is recommended for endoscope reprocessing.
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