Related Experiment Video
Updated: May 12, 2026

Heterotypic Three-dimensional In Vitro Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression
Published on: August 28, 2012
Morphological and molecular basis of ovarian serous carcinoma
Daniel G Rosen1, Zhihong Zhang, Weiwei Shan
1Department of Pathology, the University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Abstract:
Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first part of this review summarizes the morphological, histological, and immunological signatures of ovarian serous carcinoma; subsequently, we review the history of the evolvement of different grading systems used in ovarian serous cancer; in the end, we focus on characterizing the genetics that underlie the 2-tiered pathways through which ovarian serous cancers are believed to arise: the low-grade and the high-grade pathways.
More Related Videos
Related Concept Videos
Oogenesis
Ovaries
On the ovarian surface, a layer of cuboidal...

