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Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
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Related Experiment Video

Updated: May 12, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

Clostridium difficile infections in China.

Ke Jin1, Shixia Wang, Zuhu Huang

  • 1Department of Infectious Diseases, ; Jiangsu Province Key Laboratory in Infectious Diseases, ; China-US Vaccine Research Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China;

Journal of Biomedical Research
|April 5, 2013
PubMed
Summary
This summary is machine-generated.

Clostridium difficile (C. difficile) infections are a growing concern in hospitals. Current literature suggests C. difficile is present in China but not highly endemic, warranting further investigation.

Keywords:
Clostridium difficileincidenceprevalencereviewrisk factors

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Culturing and Maintaining Clostridium difficile in an Anaerobic Environment
11:13

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Published on: September 14, 2013

Related Experiment Videos

Last Updated: May 12, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment
11:13

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Published on: September 14, 2013

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Healthcare-Associated Infections

Background:

  • Clostridium difficile infection (CDI) is a significant hospital-associated infection in Western countries.
  • Limited data exists on CDI epidemiology in Chinese healthcare settings.
  • China's aging population and antibiotic overuse necessitate understanding CDI risks.

Purpose of the Study:

  • To review the current literature on Clostridium difficile infection in China.
  • To assess the epidemiological status and identify potential risk factors for CDI in China.
  • To inform prevention strategies for CDI in China and other developing nations.

Main Methods:

  • A comprehensive literature review was performed.
  • Included studies were sourced from both English and Chinese language-based journals.
  • Data synthesis focused on CDI prevalence and associated risk factors.

Main Results:

  • Available literature indicates the presence of Clostridium difficile infections in China.
  • Current evidence suggests that CDI is not particularly endemic in Chinese healthcare settings.
  • Further research is needed to confirm these preliminary findings.

Conclusions:

  • While Clostridium difficile is present in China, its endemicity requires further investigation through expanded studies.
  • Identifying specific risk factors is crucial for developing targeted prevention strategies.
  • This research is vital for mitigating the impact of CDI in China and other developing countries.