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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
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Endovascular treatment of venous occlusive disease

Tilo Kölbel1, Anders Gottsäter, Tobias Kühme

  • 1Vascular Center, Malmö University Hospital, Malmö, Sweden.

Annals of Vascular Diseases
|April 5, 2013
PubMed

Insights

Endovascular treatment effectively reopens blocked iliac veins, relieving symptoms for most patients with acute or chronic venous occlusions. This minimally invasive approach offers a promising alternative to traditional therapies for iliofemoral thrombosis.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiovascular Medicine

Background:

  • Iliac vein occlusions, both acute and chronic, cause significant patient morbidity.
  • Traditional treatments for iliofemoral thrombosis, including anticoagulation and compression, often fail to prevent post-thrombotic syndrome (PTS).
  • Medical and open surgical therapies are not always adequate for this patient group.

Purpose of the Study:

  • To evaluate the safety and efficacy of endovascular treatment for acute and chronic iliac vein occlusions.
  • To assess the potential of recanalization and stenting in restoring venous flow and alleviating symptoms.
  • To determine if endovascular methods are a superior option for acute iliofemoral thrombosis compared to conservative management.

Main Methods:

  • Endovascular techniques including balloon angioplasty and stenting were employed.
  • Catheter-directed thrombolysis (CDT) was utilized for acute iliofemoral thrombosis.
  • Patient outcomes were assessed based on restored venous flow and symptom relief.

Main Results:

  • Endovascular treatment demonstrated safety and effectiveness in managing acute and chronic iliac vein occlusions.
  • Recanalization and stenting successfully re-established normal venous flow in the iliac veins and inferior vena cava (IVC).
  • A majority of treated patients experienced symptom relief, with encouraging mid-term results.

Conclusions:

  • Endovascular treatment, including CDT with recanalization and stenting, is a viable and effective option for acute and chronic iliac vein occlusions.
  • These novel modalities offer significant benefits for patients inadequately treated by conventional therapies.
  • Further multi-center randomized prospective studies are necessary to definitively establish the role of these endovascular techniques.

Keywords:
catheter-directed thrombolysisdeep venous thrombosisiliac vein occlusionthrombolytic therapyvenous occlusive diseasevenous recanalizationvenous thromboembolism

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