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Related Experiment Video

Updated: May 12, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Urticaria multiforme.

Jason J Emer¹, Sebastian G Bernardo, Olga Kovalerchik

¹Mount Sinai School of Medicine, Department of Dermatology, New York, New York;

The Journal of Clinical and Aesthetic Dermatology

|April 5, 2013

Summary

This summary is machine-generated.

Urticaria multiforme is a rare pediatric skin condition presenting as transient wheals. Accurate diagnosis is crucial to differentiate it from similar conditions like erythema multiforme, ensuring proper patient care.

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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

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Published on: December 15, 2011

Area of Science:

Dermatology
Pediatrics
Immunology

Background:

Urticaria multiforme is a benign hypersensitivity reaction in children.
It presents with characteristic blanchable, annular wheals and acral edema.
Common misdiagnoses include erythema multiforme, serum-sickness-like reaction, and urticarial vasculitis.

Purpose of the Study:

To highlight the distinct clinical features of urticaria multiforme.
To emphasize the importance of differentiating it from other dermatological conditions.
To guide accurate diagnosis and management in pediatric patients.

Main Methods:

Case report of a four-year-old girl with urticaria multiforme.
Detailed description of clinical presentation and morphological manifestations.
Emphasis on diagnostic differentiation through history and physical examination.

Main Results:

The case illustrates the unique presentation of urticaria multiforme.
Distinguishing it from mimics like erythema multiforme is vital for appropriate care.
Clinical assessment can avoid unnecessary investigations.

Conclusions:

Urticaria multiforme requires careful clinical evaluation to distinguish from other conditions.
Accurate diagnosis leads to optimized patient management and avoids unnecessary procedures.
Recognizing this rare pediatric dermatosis is key for effective treatment.