[Sclerotic changes in bone tumors following radiation therapy]

54 cases of osteolytic bone tumors were investigated concerning sclerotic change after radiotherapy. Particular attention was paid to the frequency and the appearance time of sclerotic change, and also to the effects of sclerotic change on pathological fracture and prognosis. There was no correlation between the sclerotic change and the frequency of pathological fracture. However, the interval between radiotherapy and pathological fracture tended to be longer in the group with sclerotic change. Sclerotic change after radiotherapy is considered as a sign of good therapeutic local effect and better prognosis.