Vibrational and vibronic spectra of tryptamine conformers
Nitzan Mayorkas1, Amir Bernat, Shay Izbitski
1Department of Physics, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Abstract:
Conformation-specific ionization-detected stimulated Raman spectra, including both Raman loss and Raman gain lines, along with visible-visible-ultraviolet hole-burning spectra of tryptamine (TRA) conformers have been measured simultaneously, with the aim of obtaining new data for identifying them. The slightly different orientations of the ethylamine side chain relative to the indole lead to unique spectral signatures, pointing to the presence of seven TRA conformers in the molecular beam. Comparison of ionization-loss stimulated Raman spectra to computationally scaled harmonic Raman spectra, especially in the alkyl C-H and amine N-H stretch regions together with the retrieved information on the stabilities of the TRA conformers assisted their characterization and structural identification. The prospects and limitations of using these spectroscopic methods as potential conformational probes of flexible molecules are discussed.
More Related Videos
Related Concept Videos
IR Spectrum Peak Splitting: Symmetric vs Asymmetric Vibrations
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution
UV–Vis Spectroscopy of Conjugated Systems
One of the factors influencing λmax is the extent of conjugation in the...
¹H NMR: Interpreting Distorted and Overlapping Signals
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...
¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR
UV–Vis Spectroscopy: Molecular Electronic Transitions


