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Updated: May 12, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
Published on: August 8, 2025
Approach to the patient with an infantile hemangioma
Kristen E Holland1, Beth A Drolet
1Department of Dermatology, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Suite B260, Milwaukee, WI 53226, USA. kholland@mcw.edu
Insights
Infantile hemangiomas are common childhood tumors. While often benign, their varied presentation complicates treatment decisions and management strategies.
Area of Science:
- Pediatric Oncology
- Dermatology
- Vascular Anomalies
Background:
- Infantile hemangioma is the most common soft tissue tumor in children.
- Recent advances have improved characterization and research into these lesions.
- While often benign, they can cause significant distress, disfigurement, and morbidity.
Purpose of the Study:
- To review the current understanding of infantile hemangiomas.
- To highlight challenges in predicting treatment needs and standardizing management.
- To underscore the need for further research in this field.
Main Methods:
- Literature review of recent clinical and translational research.
- Analysis of disease spectrum, morphology, and behavior.
- Discussion of diagnostic and therapeutic challenges.
Main Results:
- Infantile hemangiomas exhibit diverse morphologies and behaviors.
- Predicting the need for intervention remains difficult.
- Standardized management approaches are challenging to establish.
Conclusions:
- Despite increased research, infantile hemangiomas present management complexities.
- Further studies are needed to refine treatment prediction and standardization.
- Addressing parental distress and cosmetic concerns is crucial.
Abstract:
Infantile hemangioma is the most common soft tissue tumor of childhood. Despite its frequency, it has only been in the last decade that these lesions have been better characterized and become the subject of significant clinical and translational research. Although most infantile hemangiomas are uncomplicated and do not require intervention, they can be a significant source of parental distress, cosmetic disfigurement, and morbidity. The wide spectrum of disease in the morphology of these lesions and in their behavior has made it difficult to predict the need for treatment and has made it challenging to establish a standardized approach to management.
