Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endurance training alters arterial baroreflex function in dogs.

P A Gwirtz1, M A Brandt, H J Mass

  • 1Department of Physiology, Texas College of Osteopathic Medicine, Fort Worth 76107-2690.

Medicine and Science in Sports and Exercise
|April 1, 1990
PubMed
Summary

Endurance exercise training significantly reduces the heart rate response of the arterial baroreflex in dogs. However, the blood pressure regulation component of this reflex remains largely unaffected by training.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of asthma in pregnancy.

Clinical medicine (London, England)·2024
Same author

Congenital Cytomegalovirus Infection: Update on Screening, Diagnosis and Treatment: Scientific Impact Paper No. 56.

BJOG : an international journal of obstetrics and gynaecology·2024
Same author

Improving paediatric antimicrobial stewardship in hospital-based settings: why, where and how?

JAC-antimicrobial resistance·2021
Same author

Repair of oesophageal atresia by consultants and supervised trainees results in similar outcomes.

Annals of the Royal College of Surgeons of England·2020
Same author

The effectiveness of influenza vaccination in pregnancy in relation to child health outcomes: Systematic review and meta-analysis.

Vaccine·2020
Same author

Quality of research: Improper evaluation of the quality of trials of retention rates.

British dental journal·2019

Area of Science:

  • Cardiovascular Physiology
  • Exercise Physiology
  • Autonomic Neuroscience

Background:

  • The arterial baroreflex is a crucial mechanism for regulating blood pressure.
  • Endurance exercise training is known to induce cardiovascular adaptations.
  • The specific impact of training on autonomic neural control of the heart during baroreflex stimulation requires further elucidation.

Purpose of the Study:

  • To investigate the effects of 12 weeks of daily exercise on the autonomic neural control of the heart during baroreflex stimulation in healthy dogs.
  • To compare baroreflex sensitivity and heart rate responses between endurance-trained and untrained dogs.

Main Methods:

  • Studied 16 untrained and 12 endurance-trained anesthetized dogs.
  • Measured arterial blood pressure (AP), carotid sinus baroreceptor pressure (CBP), electrocardiogram (ECG), heart rate (HR), and R-R interval (RR).

Related Experiment Videos

  • Assessed arterial baroreflex sensitivity during hypertension (phenylephrine), hypotension (nitroprusside), and bilateral carotid occlusion (BCO).

    • Main Results:

    • Arterial baroreflex sensitivity (delta RR/delta AP) was significantly lower in trained dogs during both hypertensive and hypotensive challenges.
    • The heart rate (HR) response to bilateral carotid occlusion (BCO) was significantly attenuated in trained dogs compared to untrained dogs.
    • The open-loop gain (Go) of the carotid baroreflex, reflecting arterial pressure regulation, was similar between trained and untrained groups.

    Conclusions:

    • Endurance training significantly reduces the heart rate component of the arterial baroreflex in dogs.
    • The arterial pressure regulatory function of the baroreflex appears to be preserved despite endurance training.
    • These findings highlight a training-induced dissociation between heart rate and blood pressure regulation within the baroreflex.