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Enzyme kinetics and relaxation measurements with surface coils
1Department of Radiology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298.
Magnetic Resonance in Medicine
|June 1, 1990
Summary
A new pulse sequence allows for selective magnetization inversion in in vivo spectroscopy. This technique enhances in vivo inversion transfer and inversion recovery experiments using advanced pulse shaping.
Area of Science:
- Magnetic Resonance Imaging
- Spectroscopy
Background:
- In vivo spectroscopy requires precise control over magnetization.
- Surface coil techniques are crucial for localized measurements.
Purpose of the Study:
- To propose a novel pulse sequence for selective magnetization inversion in in vivo surface coil spectroscopy.
- To enable advanced spectroscopic experiments like inversion transfer and recovery.
Main Methods:
- Utilizes a shaped, complex sech inversion pulse.
- Incorporates "depth pulse" phase alternation for improved selectivity.
- Designed for in vivo applications with surface coils.
Main Results:
- Achieves selective inversion of magnetization at a specific chemical shift.
- Demonstrates applicability for both in vivo inversion transfer and inversion recovery.
- Enhances the precision of localized spectroscopic measurements.
Conclusions:
- The proposed pulse sequence offers a robust method for selective magnetization manipulation in vivo.
- This technique expands the capabilities of in vivo surface coil spectroscopy.
- Facilitates more accurate and informative inversion transfer and recovery studies.