Related Experiment Video
Updated: May 12, 2026
09:31
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Multilocular cystic renal cell carcinoma: a rare entity
Atin Singhai1, Suresh Babu, Nidhi Verma
1Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India. atinsinghai@yahoo.com
BMJ Case Reports
|April 6, 2013
Summary
Multilocular cystic renal cell carcinoma (MCRCC), a rare kidney cancer subtype, typically shows a favorable prognosis. This case report details a patient with MCRCC who recovered well after nephrectomy.
Area of Science:
- Nephrology
- Oncology
- Pathology
Background:
- Multilocular cystic renal cell carcinoma (MCRCC) is a rare subtype of clear cell renal cell carcinoma.
- MCRCC accounts for only 1-2% of renal neoplasms and is associated with a favorable prognosis.
Observation:
- A 60-year-old male presented with an abdominal lump, leading to a suspicion of renal malignancy.
- Diagnostic criteria for MCRCC include an encapsulated expansile mass, entirely cystic interior with septa, and septa containing clear epithelial cells.
Findings:
- The patient underwent a nephrectomy for suspected renal malignancy.
- Postoperative follow-up at 3 months showed the patient was well, consistent with a favorable outcome.
Implications:
- This case highlights the importance of recognizing MCRCC's distinct pathological features and favorable prognosis.
- Early diagnosis and surgical management, such as nephrectomy, appear effective for MCRCC.
- Further research into MCRCC can refine diagnostic criteria and treatment strategies.
Related Concept Videos
01:28Urinary Tract Calculi I: Introduction
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
01:24Renal Tubule and Collecting Duct
The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
02:30Metastasis
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...