[Myocardial infarct following use of amphetamine derivatives]

Development of an acute myocardial infarction is described in two previously healthy men of 25 and 40 years respectively, shortly after taking oral amphetamine derivatives. Coronary angiography disclosed in both men a normal coronary system without stenoses or irregularities. Ventriculography revealed in both a segmental dysfunction of the left ventricle. A relationship is postulated between use of amphetamine and occurrence of acute myocardial infarction in the absence of coronary artery disease.