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Related Concept Videos

Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
PPE Use in Healthcare Settings II: Doffing01:10

PPE Use in Healthcare Settings II: Doffing

The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

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Related Experiment Video

Updated: May 12, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

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Published on: March 14, 2025

Iododerma following topical povidone-iodine application.

Cihangir Aliagaoglu1, Hakan Turan, Esma Uslu

  • 1Department of Dermatology, Duzce University Medical Faculty, Konuralp, Duzce, Turkey .

Cutaneous and Ocular Toxicology
|April 9, 2013
PubMed
Summary

Iododerma, a skin reaction, can rarely occur after topical povidone-iodine use. This case highlights a rare instance of iododerma developing from external application of iodine-based antiseptics.

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Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
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Area of Science:

  • Dermatology
  • Toxicology

Background:

  • Iododerma is a rare cutaneous reaction.
  • It is typically associated with systemic iodine exposure (oral or intravenous).
  • Cutaneous reactions to topical iodine antiseptics are infrequently reported.

Observation:

  • A 43-year-old male presented with two 4 cm elevated plaques with yellow-black crusts.
  • Lesions appeared 3 days prior to presentation.
  • Clinical presentation suggested a localized skin reaction.

Findings:

  • Histopathological examination confirmed the diagnosis of iododerma.
  • The patient's history revealed recent use of topical povidone-iodine.
  • The diagnosis was iododerma secondary to topical povidone-iodine application.

Implications:

  • This case underscores that topical povidone-iodine can precipitate iododerma, albeit rarely.
  • Highlights the importance of considering topical iodine exposure in the differential diagnosis of unusual skin lesions.
  • Suggests a potential delayed hypersensitivity mechanism in topical iododerma pathogenesis.