Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 12, 2026

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

Nanocomposites for bone tissue regeneration.

Nanda Gopal Sahoo¹, Yong Zheng Pan, Lin Li

¹School of Mechanical & Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.

Nanomedicine (London, England)

|April 9, 2013

Summary

Advanced nanocomposites mimic natural bone structure for tissue regeneration. These materials offer a biomimetic matrix, enhanced biological integration, and controlled delivery of growth factors, proving superior for bone repair.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Enhanced ordering in gold nanoparticles self-assembly through excess free ligands.

Langmuir : the ACS journal of surfaces and colloids·2011

Same author

Designing poly[(R)-3-hydroxybutyrate]-based polyurethane block copolymers for electrospun nanofiber scaffolds with improved mechanical properties and enhanced mineralization capability.

The journal of physical chemistry. B·2010

Same author

Variations of protein levels in human amniotic fluid stem cells CD117/2 over passages 5-25.

Journal of proteome research·2009

Same author

[Effects of Shenwu capsule and its component tetrahydroxystilbene glucoside on expression of neurotrophic factors in lumbar spinal cord of aged rats].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2009

Same author

Primary photoinduced protein response in bacteriorhodopsin and sensory rhodopsin II.

Journal of the American Chemical Society·2009

Same author

Quantitative analysis of iron concentration and expression of ferroportin 1 in the cortex and hippocampus of rats induced by cerebral ischemia.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2009

Area of Science:

Biomaterials Science
Regenerative Medicine
Nanotechnology

Background:

Natural bone is a complex nanocomposite with unique physical and biological properties.
Mimicking native bone's composition, structure, and properties is essential for effective bone tissue regeneration.
Single materials cannot replicate bone's complexity, highlighting the need for advanced biomaterials.

Purpose of the Study:

To review the composition, structure, and properties of advanced nanocomposites for bone tissue regeneration.
To discuss the biomimetic synthesis and design of bone-like nanocomposites.
To explore the application of nanocomposites in guided bone regeneration and as scaffolds.

Main Methods:

Review of literature on nanocomposite synthesis and fabrication for bone regeneration.

More Related Videos

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Related Experiment Videos

Last Updated: May 12, 2026

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Analysis of in vitro and in vivo characterization techniques for bone-mimicking nanocomposites.

Discussion of guided bone regeneration strategies using inert and bioactive nanocomposites.

Main Results:

Nanocomposites are ideal for bone regeneration due to their ability to mimic native bone's matrix environment.
They can integrate desirable biological properties and facilitate controlled, sequential delivery of multiple growth factors.
Advanced nanocomposites offer a promising platform for creating effective bone tissue regeneration strategies.

Conclusions:

Nanocomposites represent the most suitable class of materials for advanced bone tissue regeneration.
Their tunable composition and structure allow for biomimetic design and tailored biological responses.
Further research into design, fabrication, and characterization will optimize their clinical application.