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Updated: May 12, 2026

Isolation, Culture, and Transplantation of Muscle Satellite Cells
Published on: April 8, 2014
Recent progress in satellite cell/myoblast engraftment -- relevance for therapy
Deborah Briggs1, Jennifer E Morgan
1The Dubowitz Neuromuscular Centre, UCL Institute of Child Health, London, UK.
None:
There is currently no cure for muscular dystrophies, although several promising strategies are in basic and clinical research. One such strategy is cell transplantation with satellite cells (or their myoblast progeny) to repair damaged muscle and provide dystrophin protein with the aim of preventing subsequent myofibre degeneration and repopulating the stem cell niche for future use. The present review aims to cover recent advances in satellite cell/myoblast therapy and to discuss the challenges that remain for it to become a realistic therapy.
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