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Updated: May 12, 2026

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−
Published on: July 27, 2018
Structures of biomolecular ions in the gas phase probed by infrared light sources
Corey N Stedwell1, Johan F Galindo, Adrian E Roitberg
1Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. polfer@chem.ufl.edu
Abstract:
Infrared (IR) spectroscopy of biomolecular ions combines mass spectrometry's high sensitivity and ability to analyze complex mixtures with the enhanced structural information available from vibrational spectroscopy. IR spectroscopy is in principle well placed to distinguish isomers and allow chemical classification of unknown molecules. This review gives an outline of current instrumentation, spectroscopic approaches, and potential bottlenecks. We discuss the most promising applications in bioanalytical mass spectrometry in view of recent experimental results, as well as future applications based on bioinformatics.
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