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Long-term survival after operations for native and prosthetic valve endocarditis
Pearl Edlin1, Katarina Westling, Ulrik Sartipy
1Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden.
The Annals of Thoracic Surgery
|April 9, 2013
Summary
Long-term survival and early death rates were similar for patients undergoing operations for infective endocarditis (IE) in either prosthetic or native heart valves. These findings are encouraging given the rise in prosthetic valve IE cases.
Area of Science:
- Cardiology
- Cardiac Surgery
- Infectious Diseases
Background:
- Active infective endocarditis (IE) can affect both native and prosthetic heart valves.
- Surgical intervention is a critical treatment for IE.
- Understanding long-term outcomes after valve surgery for IE is essential.
Purpose of the Study:
- To compare long-term survival after operations for active IE in native versus prosthetic valves.
- To investigate differences in early mortality and postoperative complications between the two groups.
Main Methods:
- Population-based cohort study (2002-2012) of patients undergoing IE operations.
- Utilized the SWEDEHEART registry and patient records for data collection.
- Employed multivariable Cox regression to analyze survival outcomes.
Main Results:
- No significant difference in unadjusted 5-year survival between prosthetic and native valve IE (75% vs 65%).
- No significant association between prosthetic valve IE operations and death (aHR 0.83).
- Similar 30-day mortality rates for prosthetic and native valve IE (14% vs 12%).
Conclusions:
- Long-term survival is comparable for patients with prosthetic or native valve IE undergoing surgery.
- Early death and postoperative morbidity are similar between the groups.
- These findings offer reassurance as prosthetic valve IE cases increase.
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