Related Experiment Video
Updated: May 12, 2026
10:28
Reusable Single Cell for Iterative Epigenomic Analyses
Published on: February 11, 2022
Rice epigenomics and epigenetics: challenges and opportunities
1National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 430070 Wuhan, China.
Current Opinion in Plant Biology
|April 9, 2013
Summary
Rice epigenomic studies reveal DNA methylation and histone modifications influence development and stress responses. Understanding these epigenetic variations offers new ways to improve rice traits and yield.
Area of Science:
- Plant genomics
- Epigenetics
- Agricultural science
Background:
- Accumulating rice genome-wide epigenomic data, including DNA methylation and histone modifications.
- Identifying rice epigenetic regulators involved in development and stress responses.
Purpose of the Study:
- To characterize phenotypic consequences of rice epigenomic variations.
- To understand the underlying chromatin mechanisms.
- To identify epialleles linked to agronomic traits for crop improvement.
Main Methods:
- Genome-wide epigenomic analysis in rice.
- Functional studies of epigenetic regulators.
- Epigenetic variation analysis across rice varieties.
Main Results:
- Epigenetic modifications are crucial for rice genome activity.
- Epigenetic regulators impact diverse developmental and stress pathways.
- Epigenetic variations can lead to inheritable phenotypic changes.
Conclusions:
- Epigenomic variations in rice are linked to inheritable traits.
- Characterizing these variations provides strategies for enhancing rice agronomic traits.
- Understanding epigenetics can boost grain productivity in rice.
Related Concept Videos
01:46Epigenetic Regulation
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
01:37Epigenetic Regulation
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
X-chromosome...
01:46Epigenetic Regulation
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
02:32Histone Modification
The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone deacetylase,...
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone deacetylase,...
02:32Histone Modification
The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone deacetylase,...
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone deacetylase,...
02:24Ribosome Profiling
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...