Related Experiment Video
Updated: May 12, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
Published on: May 22, 2014
Roles of NLRP10 in innate and adaptive immunity
Anna Damm1, Katja Lautz, Thomas A Kufer
1Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, 50931 Cologne, Germany.
Abstract:
Mammalian nucleotide-binding domain leucine-rich repeat containing proteins (NLRs) are important pattern-recognition receptors, still the function of many NLRs remains poorly defined. Here we review first insights into the molecular function of NLRP10 highlighting the role of this specific NLR in innate and adaptive immune responses.
Related Concept Videos
NF-κB-dependent Signaling Pathway
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
Cells of the Innate Immune Response
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
Introduction to Innate and Adaptive Immunity
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
Cell-mediated Immune Responses
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Immune Surveillance by NK Cells and Phagocytes
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...

