Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Specialized Care Centers and Settings-II01:30

Specialized Care Centers and Settings-II

Rural Health Centers
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Specialized Care Centers and Settings-I01:30

Specialized Care Centers and Settings-I

Specialized care settings or centers are situated in convenient locations within the community and offer care to a specific group or population. They consist of daycare facilities, mental health facilities, rural health facilities, educational institutions, industries, shelters for the homeless, and rehabilitation facilities.
Daycare centers
They provide several functions. Some facilities care for healthy newborns and children whose parents work, while others are medically focused and care for...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improving Explainability in Clinical Mortality Prediction Using Stacking Classifiers over Annotated Clinical Notes.

Studies in health technology and informatics·2026
Same author

Cross- & multi-lingual medication detection: a transformer-based analysis.

BMC medical informatics and decision making·2025
Same author

Challenges in Multilingual Adverse Drug Reaction Detection on Social Media: Insights from Case Studies.

Studies in health technology and informatics·2025
Same author

Prediction of 90 day mortality in elderly patients with acute HF from e-health records using artificial intelligence.

ESC heart failure·2025
Same author

Do syntactic trees enhance Bidirectional Encoder Representations from Transformers (BERT) models for chemical-drug relation extraction?

Database : the journal of biological databases and curation·2022
Same author

Lessons Learned from the Usability Evaluation of a Simulated Patient Dialogue System.

Journal of medical systems·2021

Related Experiment Video

Updated: May 12, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

A controlled greedy supervised approach for co-reference resolution on clinical text.

Md Faisal Mahbub Chowdhury1, Pierre Zweigenbaum

  • 1LIMSI-CNRS, rue John von Neumann, F-91400 Orsay, France. chowdhury@fbk.eu

Journal of Biomedical Informatics
|April 9, 2013
PubMed
Summary
This summary is machine-generated.

This study improves co-reference resolution for clinical text using a mention-pair model with linguistic constraints. The novel approach achieves high F1 scores across multiple metrics and entity types, comparable to top systems.

Related Experiment Videos

Last Updated: May 12, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Area of Science:

  • Computational Linguistics
  • Natural Language Processing (NLP)
  • Biomedical Informatics

Background:

  • Co-reference resolution is crucial for NLP tasks like event linking but remains challenging.
  • Existing methods struggle with specialized domains such as clinical records.
  • Ambiguity in evaluation metrics complicates co-reference resolution research.

Purpose of the Study:

  • To present an improved mention-pair model for co-reference resolution.
  • To enhance performance on clinical text by addressing limitations of current methodologies.
  • To develop a system that performs well across various entity types and evaluation metrics.

Main Methods:

  • A variant of the mention-pair model for co-reference resolution was developed.
  • Linguistically and semantically motivated constraints were used to refine training and test instances.
  • Aggressive greedy strategies were incorporated into the chain clustering process.

Main Results:

  • The proposed approach achieved an unweighted average F1 score of 0.895 on the i2b2/VA 2011 challenge corpus.
  • Performance was comparable to the best systems participating in the challenge.
  • High average F1 scores were obtained for individual chain types: Test (0.897), Person (0.852), PROBLEM (0.855), and TREATMENT (0.884).

Conclusions:

  • The proposed co-reference resolution system demonstrates strong performance, particularly in the clinical domain.
  • The method effectively balances performance across different evaluation metrics (MUC, B(3), CEAF) and entity types.
  • This approach offers a robust solution for co-reference resolution challenges in specialized text domains.