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Updated: May 12, 2026

NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose
Published on: December 30, 2025
A non-enzymatic glucose sensor based on the composite of cubic Cu nanoparticles and arc-synthesized multi-walled
Jiang Zhao1, Liangming Wei, Chonghao Peng
1Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China.
Abstract:
A sort of non-enzymatic glucose sensor is fabricated based on a composite of cubic Cu nanoparticles and arc-synthesized multi-walled carbon nanotubes (MWCNTs) by using a substrate-enhanced electroless deposition (SEED) method. The common glassy carbon (GC) electrode is replaced by the cylindrical deposit that contains abundant MWCNTs as a support electrode. These cylindrical deposits can be synthesized by arc discharge in low pressure air atmosphere. The Cu-MWCNTs electrode shows significantly electrocatalytic activity to the oxidation of glucose in 0.1M NaOH alkaline solution. The amperometric responses to glucose reveal that the fast response achieves within 1s, the sensitivity is 922μAmM(-1)cm(-2) with a wide linear in the 0.5-7.5mM concentration range, and the detection limit is 2.0μM. The sensor also exhibits high stability and specificity to glucose. Due to the simplicity of the sensor preparation, Cu-MWCNTs electrodes are a good candidate for reliable glucose determination.

