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Activation of transposable elements during aging and neuronal decline in Drosophila

Wanhe Li1, Lisa Prazak, Nabanita Chatterjee

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.

Nature Neuroscience
|April 9, 2013
PubMed

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Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...